Evidence Based Article/annotative Bibliography On Oxygen – Article Example

Annotated Bibliography Minai, O.A., Pandya, C.M., Golish, J.A., Avecillas, J.F., McCarthy, K., Marlow, S., and Arroliga, A.C. (2007). Predictors of Nocturnal Oxygen Desaturation in Pulmonary Arterial Hypertension. Chest, 131, 109-117.
The article by Minai, Pandya, Golish et al (2007) is about a cross-sectional study conducted by them at the Cleveland Clinic. The purpose of the study was to ascertain the predictors of nocturnal desaturation in patients with pulmonary hypertension. The need for such a study arises because of the detrimental effects of hypoxia subsequent to sleep related respiratory compromise in those with lung disease and hence identification of nocturnal desaturation is very essenntial to prevent hypoxia-related complications. Patients eligible for the study were enrolled after taking consent. Appropriate data pertaining to the patients and their disease like demographics, pulmonary function, hemodynamics and functional capacity was collected in the clinic. Nocturnal desaturation was established by continuous pulse oximetry during sleep in their homes. The study was conducted on 43 patients, of which 36 were women and 7 were men. 88 percent of the patients had idiopathic pulmonary arterial hypertension. From the results it was evident that the predictors of nocturnal desaturation are old age, high hemoglobin, high brain natriuretic protein, low cardiac index, high pulmonary vascular pressure, high mean atrial pressure and moderate to severe right ventricular dilation. The authors opined that overnight oximetry must be included as a routine workup in patients with pulmonary arterial hypertension and absent exertional desaturation. The authors are from the Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland Clinic, Cleveland, OH. The first author is a pulmonologist and has published several research articles in the field of pulmonology in reputed journals. Thus it can be said that the authors of the article are valid. The article is intended to educate health professionals dealing with patients with pulmonary hypertension about the importance of identifying nocturnal hypoxia which may go unrecognised in those with absent exertional dysnoea.